One person was killed and 40 others injured when a coach and lorry crashed in fog on a motorway.
Two people were seriously hurt in the accident near Frankley Services on the M5 in the West Midlands.
Forty people were treated at the scene, on the southbound carriageway between junctions three and four.
Police said the death and one serious injury were from the coach, and the driver of the lorry was also in a serious condition. No children were involved.
Emergency services were called at 6.24am via a 999 call to reports of a serious accident.
West Midlands Ambulance Service said 27 of the injured people had been taken to various hospitals around the region - Queen Elizabeth, City and Sandwell hospitals in Birmingham, and Alexandra Hospital, Redditch.
Assistant chief ambulance officer Steve Wheaton told Sky News: "It was a very foggy stretch of road this morning. Police are investigating the exact cause, but the weather has not been helpful."
Several ambulances, rapid response vehicles and a hazardous area response team were sent to the scene, with doctors and ambulance officers.
Eye witness Paul Guppy told BBC News that there were fog patches on the motorway at the time of the crash.
"There were fog patches, because I was driving through it with my fog lights on. That area is renowned for having fog, there's a lot of low-lying land."